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NSAID consists of different classes of medications that mask your perception of irritability, stiffness, discomfort, puffiness but have no curative properties. When taken while continuing participation in strenuous activities, you can continue these irritating activities, work levels, and sports causing more damage and appreciating increased discomfort as the medication levels decrease. This indicates these medications are doubled edged since also decreasing symptoms but allowing tolerance to levels of destructive forces. Representatives of each class can be offered as a trial to evaluate it’s efficacy since each individual has different chemistry therefore result. Advil, Aleve, Lodine, Relafen, Daypro, Mobic, Celebrex, Feldene, Indocin,and Aspirin are representative. When any class of anti-inflammatories utilized over several months, monitoring of several body systems is required to prevent permanent end organ tissue injury. Concern is present for proteinuria (renal-kidney), elevated hepatic enzymes (hepatic-liver), skin rashes, allergis reactions, and GI dysfunction. The Gastrointestinal system may exhibit symptoms ranging from gastrirtis, diarrhea, nausea, vomitimg, melena, hemtochezia, to dangerous ulcerations and perforations. Read carefully the inserts included in all classes of NSIAD appreciating similar concerns and warnings. Since these anti-inflammatories for only mask and offer no potential of healing, with any irritating changes, cessation of these medications is recommended. If taking anticoagulants, use of non steriodal anti-inflammatory are contraindicated due to effects on the bleeding cascade system.
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